5. Dr. Anton Phibes (The Abominable Dr. Phibes): As the hideously disfigured Phibes, not only does Vincent Price hold a mastery over the sciences, but also the organ and when he's not plotting his revenge over the men he blames for the death of his wife he's rocking it out on the keys. All Price Fiends get to Phibes eventually, it's a psychedelic treat for our favorite mustachio.
4. Dr. Herbert West (Re-Animator): The charm of Jeffrey Combs' Dr. West is his outstanding ability as an A-Hole. He's confident, brash, and he thinks you're stupid. But when he kills & resurrects your cat using his green mojo juice he's also kind enough not to just leave you a note but to reveal the situation to you personally. And then he'll convince you to join in his Lazarus endeavor. Oh, that scamp.
3. Dr. Emilio Lizardo (The Adventures of Buckaroo Banzai Across The 8th Dimension): To be fair, the villainous actions committed by Lizardo are actually the result of the vile Lord John Whorfin inhabiting his body after the excitable scientist accidentally breached the prison of the 8th Dimension. This alien presence gives John Lithgow plenty of room to ACT to the Heavens; screaming, hollering, and hitting a new level of insane that my child brain at the time just couldn't quite understand. Now, I just laugh my ass off as he butts heads with Peter Weller's King of Cool, Buckaroo Banzai.
2. Dr. Moreau (Island of Lost Souls): Definitely the most disgusting Mad Scientist on this list, Charles Laughton's snivelly, plump suited doc is more beastly than all his Beast Men combined. Every time he slides onto screen I want to punch him in the face. And shave off that damn facial hair.
--Brad
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